Articles

Publications scientifiques

Publications on common studies

 

Full papers

 

Vanderschueren-Lodeweyckx M, Wolter R, Malvaux P, Eggermont E, Eeckels R.

The glucagon stimulation test: effect on plasma growth hormone and on immunoreactive insulin, cortisol, and glucose in children.

J Pediatr, 1974, 85:182-7

. http://www.ncbi.nlm.nih.gov/pubmed/4842794

 

 

Wolter R, Noël P, De Cock P, Craen M, Ernould C, Malvaux P, Verstaeten F, Simons J, Mertens S, Van Broeck N, Vanderschueren-Lodeweyckx M

Neuropsychological study in treated thyroid dysgenesis

Acta Paediatr Scand 1979 ; S227 :41-46.

http://www.ncbi.nlm.nih.gov/pubmed/295565

 

 

Bourguignon JP, Vanderschueren-Lodeweyckx M, Wolter R, Malvaux P, Craen M, Du Caju MV, Ernould C, Franchimont P.

Hypopituitarism and idiopathic delayed puberty: a longitudinal study in an attempt to diagnose gonadotropin deficiency before puberty.

J Clin Endocrinol Metab. 1982 54 : 33-44

http://www.ncbi.nlm.nih.gov/pubmed/6460780

 

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Van Vliet G, Bosson D, Robyn C, Craen M, Malvaux P, Vanderschueren-Lodeweyckx M, Wolter R.

Effect of growth hormone-releasing factor on plasma growth hormone, prolactin and somatomedin C in hypopituitary and short normal children.

Horm Res. 1985;22:32-45.

http://www.ncbi.nlm.nih.gov/pubmed/3928475

 

 

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Bourguignon JP, Vandeweghe M, Vanderschueren-Lodeweyckx M, Malvaux P, Wolter R, Du Caju M, Ernould C.

Pubertal growth and final height in hypopituitary boys: a minor role of bone age at onset of puberty.

J Clin Endocrinol Metab. 1986 63(2):376-82

http://www.ncbi.nlm.nih.gov/pubmed/3722327

 

http://dx.doi.org/10.1210/jcem-63-2-376

 

 

 

Bourguignon JP, Van Vliet G, Vandeweghe M, Malvaux P, Vanderschueren-Lodeweyckx M, Craen M, Du Caju MV, Ernould C.

Treatment of central precocious puberty with an intranasal analogue of GnRH (Buserelin).

Eur J Pediatr. 1987 Nov;146(6):555-60.

 

http://www.ncbi.nlm.nih.gov/pubmed/3123239

 

 

Van Vliet G, Bosson D, Craen M, Du Caju MV, Malvaux P, Vanderschueren-Lodeweyckx M.

Comparative study of the lipolytic potencies of pituitary-derived and biosynthetic human growth hormone in hypopituitary children.

J Clin Endocrinol Metab. 1987 Nov;65(5):876-9

http://www.ncbi.nlm.nih.gov/pubmed/3667884

 

 

 

Van den Broeck J, Vanderschueren-Lodeweyckx M, Malvaux P, Craen M, Van Vliet G, Dooms L, Eggermont E.

Growth hormone deficiency: a hidden obstetrical trauma

Eur J Obstet Gynecol Reprod Biol. 1987, 26:329-34

http://www.ncbi.nlm.nih.gov/pubmed/3691942

 

 

 

Vanderschueren-Lodeweyckx M, Van den Broeck J, Wolter R, Malvaux P

Early initiation of growth hormone treatment: influence on final height.

Acta Paediatr Scand Suppl, 1987, 337:4-11.

http://www.ncbi.nlm.nih.gov/pubmed/3324638

 

 

 

Bourguignon JP, Heinrichs C, Van Vliet G, Vandeweghe M, Vanderschueren-Lodeweyckx M,Malvaux P, Du Caju M, Craen M, Lambrechts L, Delire M, et al.

Evaluation and significance of the degree of pituitary-gonadal inhibition during intranasal administration of buserelin.

Acta Endocrinol (Copenh). 1987 Dec;116(4):519-25

http://www.ncbi.nlm.nih.gov/pubmed/3122484

 

 

Bourguignon JP.

Variations in duration of pubertal growth: a mechanism compensating for differences in timing of puberty and minimizing their effects on final height. Belgian Study Group for Paediatric Endocrinology.

Acta Paediatr Scand Suppl, 1988, 347:16-24.

http://www.ncbi.nlm.nih.gov/pubmed/3254030

 

 

Massa G, Vanderschueren-Lodeweyckx M, Van Vliet G, Craen M, de Zegher F, Eggermont E

Hypothalamo-pituitary dysfunction in congenital toxoplasmosis.

Eur J Pediatr, 1989, 148:742-4.

 http://www.ncbi.nlm.nih.gov/pubmed/2792124

 

 

Vanderschueren-Lodeweyckx M, Massa G, Maes M, Craen M, van Vliet G, Heinrichs C, Malvaux P.

Growth-promoting effect of growth hormone and low dose ethinyl estradiol in girls with Turner’s syndrome.

J Clin Endocrinol Metab. 1990 ;70:122-6

http://www.ncbi.nlm.nih.gov/pubmed/2294126

Bourguignon JP, Van Vliet G, in collaboration with the Belgian Study Group for Pediatric Endocrinology.

Factors influencing final height in growth hormone-treated patients.

In: Hormonal Regulation of Growth. Frisch H, Thorner MO (eds), Serono Symposia Volume 58, Raven Press, 1989, pp. 261-271.

 

Bourguignon JP, Vandeweghe M, Vanderschueren-Lodeweyckx M, Lambrechts L, Craen M, du Caju MVL, van Vliet G, Ernould C, Malvaux P.

Hypopituitarism as a model of the relative effects of sex steroids and growth hormone on the pubertal growth spurt and final height.

In: Control of the Puberty III. Delemarre-van de Waal HA, Plant TM, van Rees GP, Schoemaker J (eds). Excerpta Medica, Internal Congress Series 861, 1989; pp. 329-342.

 

Massa G, Vanderschueren-Lodeweyckx M, Craen M, Vandeweghe M, van Vliet G.

Growth hormone treatment of Turner syndrome patients with insufficient growth hormone response to pharmacological stimulation tests.

Eur J Pediatr. 1991 ; 15):460-3

http://www.ncbi.nlm.nih.gov/pubmed/1915494

 

 

Massa G, Malvaux P, Vanderschueren‑Lodeweyckx M.

Spontaneous growth in Turner syndrome: the Belgian experience.

In: Ranke MB, Rosenfeld RG (eds) Turner’s syndrome: Growth promoting therapies. Elsevier Science Publishers B.V. 1991: pp. 95‑99.

 

Vanderschueren‑Lodeweyckx M, Massa G, Maes M, Malvaux P, Heinrichs C, Craen M.

Growth promoting effect of growth hormone and low dose ethinyl estradiol in girls with Turner syndrome: 2 year results.

In: Ranke MB, Rosenfeld RG (eds) Turner’s syndrome: Growth promoting therapies. Elsevier Science Publishers B.V. 1991, pp. 257‑261.

 

Chanoine JP, Vanderschueren-Lodeweyckx M, Maes M, Thiry-Counson G, Craen M, Van Vliet G.

Growth hormone (GH) treatment in short normal children: absence of influence of time of injection and resistance to GH autofeedback.

J Clin Endocrinol Metab. 1991 ; 73:1269-75.

http://www.ncbi.nlm.nih.gov/pubmed/1955508

 

 

 

de Zegher F, Vanderschueren-Lodeweyckx M, Heinrichs C, Van Vliet G, Malvaux P.

Thyroid dyshormonogenesis: severe hypothyroidism after normal neonatal thyroid stimulating hormone screening.

Acta Paediatr, 1992, 81:274-6

. http://www.ncbi.nlm.nih.gov/pubmed/1511207

 

 

Massa G, Maes M, Heinrichs C, Vandeweghe M, Craen M, Vanderschueren-Lodeweyckx M.

Influence of spontaneous or induced puberty on the growth promoting effect of treatment with growth hormone in girls with Turner’s syndrome.

Clin Endocrinol (Oxf). 1993; 38:253-60

http://www.ncbi.nlm.nih.gov/pubmed/8458097

 

 

 

Massa G, Vanderschueren‑Lodeweyckx M.

Growth promoting effect of growth hormone and low dose ethinylestradiol in girls with Turner syndrome: 4 year results.

In: Hibi I, Takano K (eds) Basic and clinical approach to Turner syndrome. Elsevier Science Publishers B.V. 1993, pp. 327‑332.

 

 

Bourguignon JP, Pierard GE, Ernould C, Heinrichs C, Craen M, Rochiccioli P, Arrese JE, Franchimont C.

Effects of human growth hormone therapy on melanocytic naevi.

Lancet, 1993, 341:1505-6.

http://www.ncbi.nlm.nih.gov/pubmed/8099381

 

 

Heinrichs C, Craen M, Vanderschueren-Lodeweyckx M, Malvaux P, Fawe L, Bourguignon JP.

Variations in pituitary-gonadal suppression during intranasal buserelin and intramuscular depot-triptorelin therapy for central precocious puberty. Belgian Study Group for Pediatric Endocrinology.

Acta Paediatr. 1994 ; 83:627-33

http://www.ncbi.nlm.nih.gov/pubmed/7919761

 

 

De Schepper J, Craen M, Massa G, Heinrichs C, Maes M, Du Caju M, Rausin L, Bourguignon JP.

Growth hormone therapy in Turner’s syndrome: one versus two daily injections.

J Clin Endocrinol Metab. 1994;79:489-94

http://www.ncbi.nlm.nih.gov/pubmed/8045968

 

 

 

de Zegher F, Maes M, Heinrichs C, Thiry G, Du Caju MV, De Schepper J, Craen M, Chanoine JP, Dooms L, Malvaux P.

 

High-dose growth hormone therapy for short children born small for gestational age. Belgian Study Group for Paediatric Endocrinology.

 

Acta Paediatr Suppl, 1994, 399:77; discussion 78.

http://www.ncbi.nlm.nih.gov/pubmed/7949623

 

 

Heinrichs C., De Schepper J., Thomas M., Massa G., Craen M., Malvaux P., Ernould C., François I., Du Caju M., Vandeweghe M., Thiry-Counson G., Maes M., Bourguignon J.P.

Final height in 46 girls with Turner syndrome treated with growth hormone in Belgium: evaluation of height recovery and predictive factors

In: Turner syndrome in a life span : Perspective: Research and Clinical Aspects. Eds Albertsson-Wikland K. and Ranke M., Elsevier Science, 1995, pp. 137-147.

 

 

de Zegher F, Maes M, Gargosky SE, Heinrichs C, Du Caju MV, Thiry G, De Schepper J, Craen M, Breysem L, Löfström A, Jönsson P, Bourguignon JP, Malvaux P, Rosenfeld RG.

High-dose growth hormone treatment of short children born small for gestational age.

J Clin Endocrinol Metab. 1996;81:1887-92

http://www.ncbi.nlm.nih.gov/pubmed/8626853

 

 

De Schepper J, Otten BJ, François I, Bourguignon JP, Craen M, Van der Burgt I, Massa GG.

Growth hormone therapy in pre-pubertal children with Noonan syndrome: first year growth response and comparison with Turner syndrome.

Acta Paediatr. 1997;8):943-6

http://www.ncbi.nlm.nih.gov/pubmed/9343272

 

 

Maes M, Vandeweghe M, Du Caju M, Ernould C, Bourguignon J-P, Massa G.

A valuable improvement of adult height prediction methods in short normal children.

Horm Res 1997; 48:184-190.

http://www.ncbi.nlm.nih.gov/pubmed/9378465

 

Xhrouet-Heinrichs D, Lagrou K, Heinrichs C, Craen M, Dooms L, Malvaux P, Kanen F, Bourguignon JP.

 

Longitudinal study of behavioral and affective patterns in girls with central precocious puberty during long-acting triptorelin therapy.

Acta Paediatr. 1997;86:808-15

http://www.ncbi.nlm.nih.gov/pubmed/9307158

 

 

Lagrou K, Xhrouet-Heinrichs D, Heinrichs C, Craen M, Chanoine JP, Malvaux P, Bourguignon JP.

Age-related perception of stature, acceptance of therapy, and psychosocial functioning in human growth hormone-treated girls with Turner’s syndrome.

J Clin Endocrinol Metab. 1998;83:1494-501

http://www.ncbi.nlm.nih.gov/pubmed/9589645

 

 

Lagrou K, Xhrouet-Heinrichs D, Bourguignon JP.

Deviations in growth and pubertal development and their treatment. How consistent are patient’s and physician’s outlooks ?

In : Growth, stature and psychosocial well-being. Eiholzer, Haverkamp & Voss, eds. Hogrefe & Huber publishers, 1999, pp. 131-136.

 

Thomas M, Maes M, Ernould E, Bourguignon JP.

L’insuffisance en hormone de croissance : étiologie et révision diagnostique après la fin de la croissance.

Journal du Pédiatre Belge 1999 ; 1 :155-160.

 

De Schepper J, François I, Vanbesien J, Thomas M.

Groeihormoon behandeling bij kinderen met een Noonan syndroom : de belgische ervaring na twee jaren ononderbroken toediening.

Tijdschr Belg Kinderarts 1999,1 :173-176.

 

Lebrethon MC, Bourguignon JP.

Statégie diagnostique devant un retard de croissance.

Journal du Pédiatre Belge 1999 ; 1 :181-185.

 

Heinrichs C, De Schepper J, Massa G, Thomas M, Verlinden F, Craen M, Malvaux P, François I, Du Caju M, Vandeweghe M, Maes M, Bourguignon JP.

Le traitement par hormone de croissance dans le syndrome de Turner: l’expérience du B.S.G.P.E.

Journal du Pédiatre Belge 1999 ; 1 : 177-180.

 

Thomas M, Bourguignon JP, Craen M, De Schepper J, de Zegher F, Dooms L, Du Caju M, François I, Heinrichs C, Malvaux P, Massa G, Rooman R, Thiry- Counson G, Vandeweghe M, Maes M.

Réponse au traitement par hormone de croissance (GH) et taille adulte dans l’insuffisance idiopathique en GH: expérience du Belgian Study Group for Paediatric Endocrinology (BSGPE).

Journal du Pédiatre Belge 1999 ; 1 :161-168.

 

Heinrichs C, de Zegher F.

L’enfant avec retard de croissance intra-utérin: quelle évolution staturale postnatale? quelles perspectives thérapeutiques en l’absence de rattrapage spontané?

Journal du Pédiatre Belge 1999 ; 1: 169-172.

 

Krstevska-Konstantinova M, Beckers D, Craen M, De Schepper J, de Zegher F, Du Caju M, François I, Heinrichs C, Lagrou K, Maes M, Malvaux P, Xhrouet-Heinrichs D, Bourguignon JP

. La puberté précoce centrale et son traitement: l’expérience du B.S.G.P.E.

Journal du Pédiatre Belge 1999 ; 1 : 186-190.

 

Lagrou K, Xhrouet-Heinrichs D, Craen M, Chanoine JP, De Schepper J, de Zegher F, Dooms L, Ernould C, Heinrichs C, Malvaux P, Vandeweghe M, Bourguignon JP.

Que nous apprend l’évaluation psychologique des enfants et adolescents de petite taille traités par hormone de croissance?

Journal du Pédiatre Belge 1999 ; 1 :191-194.

 

de Zegher F, Du Caju MV, Heinrichs C, Maes M, De Schepper J, Craen M, Vanweser K, Malvaux P, Rosenfeld RG

 

 

Early, discontinuous, high dose growth hormone treatment to normalize height and weight of short children born small for gestational age: results over 6 years.

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J Clin Endocrinol Metab. 1999;84:1558-61

http://www.ncbi.nlm.nih.gov/pubmed/10323379

 

 

 

Lagrou K, Xhrouet-Heinrichs D, Massa G, Vandeweghe M, Bourguignon JP, De Schepper J, de Zegher F, Ernould C, Heinrichs C, Malvaux P, Craen M.

 

Quality of life and retrospective perception of the effect of growth hormone treatment in adult patients with childhood growth hormone deficiency.

J Pediatr Endocrinol Metab. 2001;14 Suppl 5:1249-60; discussion 1261-2

http://www.ncbi.nlm.nih.gov/pubmed/11964020

 

 

Thomas M, Massa G, Bourguignon JP, Craen M, De Schepper J, de Zegher F, Dooms L, Du Caju M, François I, Heinrichs C, Malvaux P, Rooman R, Thiry-Counson G, Vandeweghe M, Maes M.

 

Final height in children with idiopathic growth hormone deficiency treated with recombinant human growth hormone: the Belgian experience.

 

Horm Res, 2001; 55:88-94.

http://www.ncbi.nlm.nih.gov/pubmed/11509865

 

 

Krstevska-Konstantinova M, Charlier C, Craen M, Du Caju M, Heinrichs C, de Beaufort C, Plomteux G, Bourguignon JP.

 

Sexual precocity after immigration from developing countries to Belgium: evidence of previous exposure to organochlorine pesticides.

 

Hum Reprod, 2001, 5:1020-6

http://www.ncbi.nlm.nih.gov/pubmed/11331654

http://humrep.oxfordjournals.org/content/16/5/1020.long

 

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Massa G, Thomas M.

 

Groeihormoonbehandeling bij kinderen anno 2002.

 

Tijdschr Geneeskd 2002; 58 :1463-1469.

 

 

Massa GGVerlinde VHeinrichs CBelgian Study Group of Pediatric Endocrinology.

 

Screening for Turner’s syndrome by chromosome analysis of all girls with short stature.

 

J Pediatr. 2002 Jan;140(1):141-2

http://www.ncbi.nlm.nih.gov/pubmed/11838440

 

Thomas M, Massa G, Maes M, Beckers D, Craen M, Francois I, Heinrichs C, Bourguignon JP.

 

Growth hormone (GH) secretion in patients with childhood-onset GH deficiency retesting after one year of therapy and at final height.

 

Horm Res, 2003; 59:7-15.

http://www.ncbi.nlm.nih.gov/pubmed/12566729

 

 

Massa G, Heinrichs C, Verlinde S, Thomas M, Bourguignon JP, Craen M, Francois I, Du Caju M, Maes M, De Schepper J.

 

Late or delayed induced or spontaneous puberty in girls with Turner syndrome treated with growth hormone does not affect final height.

 

J Clin Endocrinol Metab, 2003; 88:4168-74.

http://www.ncbi.nlm.nih.gov/pubmed/12970282

 

 

Verlinde F, Massa G, Lagrou K, Froidecoeur C, Bourguignon JP, Craen M, De Schepper J, Du Caju M, Heinrichs C, Francois I, Maes M; Belgian Study Group of Paediatric Endocrinology.

 

Health and psychosocial status of patients with Turner syndrome after transition to adulthood: the Belgian experience.

 

Horm Res. 2004; 62(4):161-7.

http://www.ncbi.nlm.nih.gov/pubmed/15297800

 

Thomas M, Massa G, Craen M, de Zegher F, Bourguignon JP, Heinrichs C, De Schepper J, Du Caju M, Thiry-Counson G, Maes M.

 

Prevalence and demographic features of childhood growth hormone deficiency in Belgium during the period 1986-2001.

 

Eur J Endocrinol 2004; 151:67-72

http://www.ncbi.nlm.nih.gov/pubmed/15248824

 

 

Massa G, Verlinde F, De Schepper J, Thomas M, Bourguignon JP, Craen M, de Zegher F, Francois I, Du Caju M, Maes M, Heinrichs C.

Trends in age at diagnosis of Turner syndrome.

Arch Dis Child 2005;90:267-8.

http://www.ncbi.nlm.nih.gov/pubmed/15723912

 

 

Maes M, Thomas M et le Belgian Study Group for Pediatric Endocrinology.

L’insuffisance en hormone de croissance : un diagnostic pas toujours évident ?

Percentile 2005; 10:

 

Lagrou K, Froidecoeur C, Verlinde F, Craen M, De Schepper J, Francois I, Massa G;

The Belgian Study Group of Paediatric Endocrinology. Psychosocial functioning, self-perception and body image and their auxologic correlates in growth hormone and oestrogen-treated young adult women with Turner syndrome.

Horm Res. 2006;66(6):277-84.

 http://www.ncbi.nlm.nih.gov/pubmed/16946621

http://www.karger.com/Article/FullText/95547

 

Anckaert E, Schiettecatte J, Vanbesien J, Smitz J, Velkeniers B, De Schepper J.

Variability among five different commercial IGF-1 immunoassays in conditions of childhood-onset GH deficiency and GH therapy.

Acta Clin Belg. 2006;61(6):335-9.

http://www.ncbi.nlm.nih.gov/pubmed/17323843

http://dx.doi.org/10.1179/acb.2006.053

 

 

Louis O, Verlinde S, Thomas M, De Schepper J.

Between-centre variability versus variability over time in DXA whole body measurements evaluated using a whole body phantom.

Eur J Radiol. 2006;58(3):431-4

http://www.ncbi.nlm.nih.gov/pubmed/16513312

 

 

 Lagrou K, Vanderfaeillie J, Froidecoeur C, Thomas M, Massa G, Tenoutasse S, Craen M, Lebrethon MC, Beckers D, Francois I, Rooman R, Thiry-Counson G, de Beaufort C, De Schepper J. Effect of 2 years of high-dose growth hormone therapy on cognitive and psychosocial development in short children born small for gestational age.

Eur J Endocrinol. 2007;156(2):195-201.

http://www.ncbi.nlm.nih.gov/pubmed/17287409

http://eje-online.org/content/156/2/195.full.pdf

 

Lagrou K, Froidecoeur C, Thomas M, Massa G, Beckers D, Craen M, de Beaufort C, Rooman R, François I, Heinrichs C, Lebrethon MC, Thiry-Counson G, Maes M, De Schepper J.

Concerns, expectations and perception regarding stature, physical appearance and psychosocial functioning before and during high-dose growth hormone treatment of short children born small for gestational age.

Horm Res. 2008;69(6):334-42

http://www.ncbi.nlm.nih.gov/pubmed/18504392

http://www.karger.com/Article/FullText/117389

 

 

De Schepper J, Thomas M, Beckers D, Craen M, Maes M, de Zegher F.

Growth hormone treatment and fat distribution in children born small for gestational age.

J Pediatr. 2008 Mar;152(3):327-30.

 http://www.ncbi.nlm.nih.gov/pubmed/18280835

 

 

 

Noordam C, Peer PG, Francois I, De Schepper J, van den Burgt I, Otten BJ.

Long-term GH treatment improves adult height in children with Noonan syndrome with and without mutations in protein tyrosine phosphatase, non-receptor-type 11.

Eur J Endocrinol. 2008 159(3):203-8.

http://www.ncbi.nlm.nih.gov/pubmed/18562489

http://eje-online.org/content/159/3/203.full.pdf

 

 

Jung H, Land C, Nicolay C, De Schepper J, Blum WF, Schönau E.

Growth response to an individualized versus fixed dose GH treatment in short children born small for gestational age: the OPTIMA study.

Eur J Endocrinol. 2009 Feb;160(2):149-56

http://www.ncbi.nlm.nih.gov/pubmed/19039085

http://eje-online.org/content/160/2/149.full.pdf

 

 

Beckers D, Thomas M, Jamart J, Francois I, Maes M, Lebrethon MC, De Waele K, Tenoutasse S, De Schepper J.

Adult final height after growth hormone therapy for irradiation-induced growth hormone deficiency in childhood survivors of brain tumours: the Belgian experience.

Eur J Endocrinol. 2010;162(3):483-490

 

http://www.ncbi.nlm.nih.gov/pubmed/19969557

http://eje-online.org/content/162/3/483.full.pdf

 

 

Verlinde F, De Schepper J.

De medische en sociale situatie van jonge vrouwen met het syndroom van Turner in België.

Tijdschr. Voor Geneeskunde 2011, 67(11): 526-531

 

 

De Schepper JRasmussen MHGucev ZEliakim ABattelino T

Long-acting pegylated human GH in children with GH deficiency: a single-dose, dose-escalation trial investigating safety, tolerability, pharmacokinetics and pharmacodynamics.

 

Eur J Endocrinol. 2011;165(3):401-9.

http://www.ncbi.nlm.nih.gov/pubmed/21724838

 

 

Descamps OS, Tenoutasse S, Stephenne X, Gies I, Beauloye V, Lebrethon MC, De Beaufort C, De Waele K, Scheen A, Rietzschel E, Mangano A, Panier JP, Ducobu J, Langlois M, Balligand JL, Legat P, Blaton V, Muls E, Van Gaal L, Sokal E, Rooman R, Carpentier Y, De Backer G, Heller FR.

Management of familial hypercholesterolemia in children and young adults: consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization.

BSGPE workgroup

Atherosclerosis. 2011 ;218(2):272-80.

http://www.ncbi.nlm.nih.gov/pubmed/21762914

 

 http://www.atherosclerosis-journal.com/article/S0021-9150(11)00497-7/fulltext

 

 

Gies I, Thomas M, Tenoutasse S, De Waele K, Lebrethon MC, Beckers D, Francois I, Maes M, Rooman R, de Beaufort C, Massa G, De Schepper J.

Insulin sensitivity modulates the growth response during the first year of high-dose growth hormone treatment in short prepubertal children born small for gestational age.

Horm Res Paediatr. 2012;78(1):24-30.

http://www.ncbi.nlm.nih.gov/pubmed/22832126

 

Sävendahl L, Maes M, Albertsson-Wikland K, Borgström B, Carel JC, Henrard S, Speybroeck N, Thomas M, Zandwijken G, Hokken-Koelega A.

Long-term mortality and causes of death in isolated GHD, ISS, and SGA patients treated with recombinant growth hormone during childhood in Belgium, The Netherlands, and Sweden: preliminary report of 3 countries participating in the EU SAGhE study.

J Clin Endocrinol Metab. 2012;97:E213-7.

http://www.ncbi.nlm.nih.gov/pubmed/22238393

http://press.endocrine.org/doi/pdf/10.1210/jc.2011-2882

 

 

 

Clayton P, Bonnemaire M, Dutailly P, Maisonobe P, Naudin L, Pham E, Zhang Z, Grupe A, Thiagalingam A, Denèfle P; EPIGROW Study Group (Kapelari K, Borkenstein M, Payer R, De Schepper J, Tenoutasse S, Rooman R, Craen M, Le Bouc Y, Colle M, Polak M, Mallet E, Petrus M, Maghnie M, Zucchini S, Loche S, Wasniewska M, Pozzan GB, Bona G, Greggio N, Garofalo P, Cappa M, Vannelli S, Bakker B, Hoekx J, Van Mil EG, van Pinxteren-Nagler E, Birkholz D, Szewczyk L, Galesanu C, Labarta JI, Echevarria IR, Argente J, Martos-Moreno GÁ, Caimari M, Sesma CP, Gomez EG, Buchanan C, Storr H, Albanese A).

Characterizing short stature by insulin-like growth factor axis status and genetic associations: results from the prospective, cross-sectional, epidemiogenetic EPIGROW study.

 J Clin Endocrinol Metab. 2013 ;98(6):E1122-30

http://www.ncbi.nlm.nih.gov/pubmed/23596138

 

 

 

Straetemans S, Roelants M, Thomas M, Rooman R, De Schepper J.

Reference curve for the first-year growth response to growth hormone treatment in prepubertal children with idiopathic growth hormone deficiency: validation of the KIGS first-year growth response curve using the Belgian Register for the Study of Growth and Puberty Problems.

 

Horm Res Paediatr. 2014 81 :343-349.

http://www.ncbi.nlm.nih.gov/pubmed/24686034

http://www.karger.com/Article/FullText/358330

 

 

Abstracts

De Schepper J, Massa G, Heinrich C, Maes M, Du Caju M, Thiry G, Rausin L

The effects of ine versus two daily injections of growth hormone in Turner syndrome.

ESPE 30th annual meeting Berlin

De Schepper Dewaele M and BSGPE

Lymphocyte subsets during growth hormone therapy in Turner syndrome

ESPE 30 th annual meeting, Berlin

 

Xhrouet-Heinrichs D, Lagrou K, Heinrichs C, Craen M, Vandeweghe M, Malvaux P, Bourguignon JP.

Self-esteem in growth-hormone-treated adolescent girls with Turner Syndrome.

 

ESPE 31th Annual Meeting, Zaragoza, 1992.

Horm Res 1992; 37:4suppl: 90

 

de Zegher F, Maes M, Heinrichs C, Thiry G, Du Caju MV, De Schepper J, Craen M, Chanoine JP, Dooms L, Malvaux P.

High-dose growth hormone therapy for short children born small for gestational age. Belgian Study Group for Paediatric Endocrinology.

 

Acta Paediatr Suppl. 1994 Apr;399:77

 

Thomas M, Massa G, Maes M, De Schepper J.

Growth promoting effect of growth hormone (GH) and final height of children with total and partial GH deficiency (GHD) compared to non-GHD short slowly growing children as judged by provocative testing.

 

LWPES/ESPE 6th Joint Meeting, Montreal.

Pediatr Res 2001; 49 [Suppl 2]:P1-412.

 

  1. Massa G, Verlinde F, Heinrichs C

The Lyon method of projected adult height for girls with Turner syndrome underestimates final height in young TS girls and overestimates final height in TS girls with spontaneous puberty

 

ESPE Meeting 2003

 

Verlinde F, Massa G, Bourguignon JP, Craen M, Du Caju M, Heinrichs C, François I, Maes M, De Schepper J.

Pubertal development and growth during puberty induction with ethinylestradiol in girls with Turner syndrome treated with growth hormone.

 

43rd Annual ESPE Meeting, September 2004.

Hormone Research 2004; 62 (suppl. 2):129 (abstr P3-459).

 

Thomas M, Massa G, Van Besien J, Tenoutasse S, Craen M, Lebtrethon MC, Beckers D, François I, Maes M, Rooman R, Thiry-Counson G, de Beaufort C, De Schepper J.

Insulin sensitivity is a major determinant of the growth hormone response to high dose growth hormone (GH) therapy in young short children born small-for-gestational age (SGA).

43rd Annual ESPE Meeting, September 2004.

Hormone Research 2004; 29 (suppl. 2):129 ( abstr. FC9-92).

 

De Schepper J, Verlinde F, Thomas M, Heinrichs C, Maes M

Bone mineralization, muscular strength and body fat accumulation at near final height in adolescents with growth hormone deficiency after growth hormone treatment

5th Joint Meeting ESPE/LWPES, Lyon.

Horm Res 2005;64 [Suppl 1]:301 (P3-1035).

 

Lagrou K, Froidecoeur C, Craen M, De Schepper J, François I, Verlinde F, Massa G.

Psychological evaluation of psychosocial functioning, self-perception and body image in young adult women with Turner Syndrome.

5th Joint Meeting ESPE/LWPES, Lyon.

Horm Res 2005;64 [Suppl 1]:66 (P1-211).

 

Lagrou K, Froidecoeur C, Craen M, De Schepper J, François I, Verlinde F, Massa G.

Satisfaction with the feminizing effects of oestrogen treatment: a psychological evaluation in young women with Turner syndrome.

5th Joint Meeting ESPE/LWPES, Lyon.

Horm Res 2005;64 [Suppl 1]:66 (P1-212).

 

De Schepper J,Thomas M, Maes M, de Zegher F

High-dose growth hormone (GH) therapy in short children born small for gestational age (SG A) is associated with a leaner body composition and a more central fat distribution

 

Hormone Res 2006; 65 S4 : 174

 

France A, Thomas M, Craen M, Francois I, De Schepper.

Final height remains reduced in GH treated children after brain irradiation.

ESPE meeting 2006

Horm Res 2006; 65 Suppl 4: 153.

 

De Schepper J, Thomas M, De Waele K, Tenoutasse S, Lebreton MC, Beckers D, Francois I, Maes M, Rooman R, Thiry-Counson G, de Beaufort C, Massa G.

Skeletal effects of high dose growth hormone treatment of short children born small for gestational age.

ESPE meeting 2007

Hormone Research 2007, 68 (S1): 153.

 

Massa G, Thomas M, Bourguignon JP, Craen M, De Schepper J, Heinrichs C, Francois I, Maes M, Rooman R.

Catch-up growth during GH treatment in children with idiopathic or congenital growth hormone deficiency is not solely due to a delay in growth plate senescence.

ESPE meeting 2007

Hormone Research 2007, 68 (S1): 169.

 

Verlinde F, Francois I, Craen M, De Schepper J, Massa G.

Monozygotic twins with Turner syndrome may respond differently to GH treatment and puberty induction.

ESPE meeting 2007

Hormone Research 2007, 68 (S1): 234.

  1. Verlinde, M. Thomas, K. De Waele, I. Gies, I Francois, D Beckers, C Brachet, MC Lebrethon, G. Counson-Thiry, G Massa, R Rooman and J De Schepper on behalf of the Belgian Study Group of Paediatric Endocrinology.

First year growth response to GH therapy in short prepubertal SGA patients: results from standard clinical practice in Belgium.

47th Annual Meeting of the ESPE 2008

Hormone Research, 2008 70 (suppl 1), 158.

 

Descamps OS, Stephenne X, Tenoutasse S, Gies I, Beauloye V, Lebrethon M-C, De Beaufort C, De Waele K, Sokal E, Carpentier Y, Langlois M, Ducobu J, De Backer G, Rooman R and Heller FR

Consensus on early management of familial hypercholesterolemia in Belgium and Luxembourg

Société Belge de Pédiatrie, Liège, 13-14 march 2009.

Belgian Lipid Club. 28 may 2009

 

De schepper J , Verlinde F, Thomas M, Heinrichs C, Maes M, Louis O, Ankaert E, Kaufmann JM

Hormonal determinants of bone mass changes after stopping GH therapy at final height in adolescents with childhood onset GH deficiency

Hormone Res 2009 72 S3

 

Bang P, Hermoso Lopez, F Polak M, Rooman R, Maisonobe P, Dutailly P and EU IGFD Group

The European Increlex® growth forum database(EU IGFD): a European subject registry for longterm

safety and efficacy monitoring

Hormone Res 2009 72 S3 506

De Schepper J, Verlinde F, Thomas M, ;Heinrichs C, Maes M, Louis O, Anckaert E, Kaufman JM

 

Hormonal determinants of bone mass changes after stopping GH therapy at final height in adolescents with childhood onset GH deficiency

 

Hormone Res 72 S3 :114

 

Gies I, Denayer E , Thomas M , De Schepper J, Race V, Legius E.

Genotype of short children with Noonan Syndrome referred for growth hormone therapy in Belgium

38 ste Jaarlijks Congres van de Belgische Vereniging voor Kindergeneeskunde. Brussel, 19-20/03/2010. (oral presentation).

(no ESPE abstracts in 2010)

 

  1. Verlinde, M. Thomas, G. Massa, C. Heinrichs, M. Craen, MC Lebrethon, I. Francois, R. Rooman, M. Maes, J. De Schepper

Adult height of growth hormone treated girls with Turner syndrome: an update of the Belgian experience.

 

ESPE meeting 2011

Horm Res 2011; 76 (suppl 2):259-260

 

Thomas M., Tenoutasse S., Cools M., Maes M., De Schepper J., Heinrichs C., Beckers D., Massa G. in collaboration with the members of BSGPE

First year growth response to growth hormone therapy in patients with short stature associated with SHOX deficiency.

 

ESPE meeting 2011

Horm Res 2011; 76 (suppl 2)

 

Straetemans S, Roelants M, Thomas M, Rooman R, De Schepper J.

Growth targets for prepubertal children with idiopathic growth hormone deficiency during the first year of growth hormone therapy.

ESPE 2012

Horm Res Paediatr 2012, , 78 , S1, 191-192

 

Verlinde F, Thomas M, Tenoutasse S, Rooman R, De Schepper J.

Growth outcome of Turner girls with 45,X/46,XY mosaicism after GH therapy.

ESPE 2012

Horm Res Paediatr 2012, 78 , S1, 129-130

 

Thomas M, François I, De Waele K, Beauloye F, France A, Brachet C, Lebrethon M.-C.,Gies I, Thiry-Counson G, Beckers D, Massa G, Verlinde F, De Schepper J.

Pubertal height gain and adult height in pre- and pubertal short SGA patients treated with GH.

9th Joint Meeting of Pediatric Endocrinology, Milan, 2013.

Hormone Res Paediatr 2013

 

Buysse W, Beauloye V, De Schepper J, Van Aken S, De Waele K, Craen R, Gies I, Francois I, Beckers D, Desloovere A, Francois G, Dhondt K, Cools M.

Evaluation of the hypothalamic-pituitary-adrenal axis and polysomnography in Prader-Willi children.

ESPE 2013

Horm Res Paediatr 2013.

 

Gies I, Cools M, De Waele K, Maes M, Beauloye V, Brachet C, Boros E, Chivu O, den Brinker M, France A, Rooman R, De Schepper J.

GH-induced short term increments of serum bone markers in children with idiopathic short stature.

ESPE 2013.

Horm Res Paediatr 2013.

 

Rooman R, France A, Heinrichs C, Tenoutasse S, Brachet C, Cools M, De Waele K, Massa G, Lebrethon MC, Bourguignon JP, Gies I, Van Besien J, De Rycke C, De Schepper J

The ZOMATRIP Study: 4 Year combination therapy of GH and GnRHa in girls with a short predicted adult height during early puberty: interim results at the end of the treatment phase

ESPE 2014

Horm Res Paediatr 2014

 

Straetemans S, Thomas M, Tenoutasse S, De Schepper J, Rooman R

First-year growth response to GH in relation to final height outcome in prepubertal children with idiopathic GH deficiency

ESPE 2014

Horm Res Paediatr 2014